pyrazoles-derivatives

Hou, Zhong-Wei published the artcileElectrophotocatalytic C-H Azolation of Arenes, HPLC of Formula: 930-36-9, the publication is ChemElectroChem (2021), 8(9), 1571-1573, database is CAplus.

An electrophotocatalytic method was developed for the dehydrogenative cross coupling of arenes with azoles employing a bicatalytic system consisting of acridinium dye and (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO). The reactions were conducted in a simple undivided cell with visible-light irradiation and requires no external chem. oxidant.

ChemElectroChem published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, HPLC of Formula: 930-36-9.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Li, He published the artcileStructural diversity and properties of four complexes with 4-acyl pyrazolone derivative, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, the publication is Polyhedron (2013), 209-215, database is CAplus.

Four {[Zn(HL)(H₂O)(DMF)](NO₃)}_n (1), [Cd(HL)₂]_n (2), {[Mn(HL)₂]·MeCN·2H₂O} (3) and {[Mn(L)(μ₂-EtOH)]}_n (4) (H₂L = N-(1-phenyl-3-methyl-4-benzal-pyrazolone-5)-nicotinic hydrazide) were synthesized and characterized by elemental analyses, IR spectra, thermal analyses and single crystal x-ray diffraction. The structural analyses reveal that complexes 1, 2 and 3, formed by H₂L with metal nitrate, have Zigzag chain, double-stranded chain and mononuclear structures, resp., and the ligands adopt three different coordination modes in these complexes. While, complex 4, formed by H₂L with Mn acetate, represents a 2-dimensional network structure with dinuclear units bridged by EtOH mols. The metal atom and counteranion have certain influences on the structures of resulting complexes. The fluorescent properties of 1 and 2 and the magnetism of 4 were studied.

Polyhedron published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Liu, Mei published the artcileSynthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors, Safety of (1H-Pyrazol-5-yl)boronic acid, the publication is Bioorganic & Medicinal Chemistry Letters (2006), 16(10), 2590-2594, database is CAplus and MEDLINE.

A novel class of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones I [R¹ = Me, Me₂CH, MeOCH₂CH₂, HO₂C(CH₂)₃, MeCONHCH₂CH₂, etc.; R² = Me, Et, Ph, HO₂CCH₂, HOCH₂CH₂, etc.; R³ = H, Cl, Ph, 3-pyrazolyl] as c-Jun-N-terminal kinase (JNK) inhibitors is described. These compounds were synthesized via the condensation of 2-nitrobenzaldehydes and hydroxypyrazoles. The structure-activity relationships (SAR) and kinase selectivity profile of the inhibitors are also discussed. Compound II was identified as a potent JNK inhibitor with good cellular potency.

Bioorganic & Medicinal Chemistry Letters published new progress about 724710-02-5. 724710-02-5 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Boronic acid and ester,Pyrazole,Boronic Acids,Boronic acid and ester, name is (1H-Pyrazol-5-yl)boronic acid, and the molecular formula is C3H5BN2O2, Safety of (1H-Pyrazol-5-yl)boronic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Cai, Dongren published the artcileDesign and synthesis of novel Bronsted-Lewis acidic ionic liquid and its application in biodiesel production from soapberry oil, Related Products of pyrazoles-derivatives, the publication is Energy Conversion and Management (2018), 318-327, database is CAplus.

With the combination of mol. simulation and relevant experiments, the efficient Bronsted-Lewis acidic ionic liquid (IL) was designed and synthesized for biodiesel production from soapberry oil. In mol. simulation, 4-methylthiazole (MT) is proved to be the best matrix for IL preparation via electrostatic potential anal. and proton affinity anal., and it also is verified by experiments In orthogonal experiment, the relationship in catalytic activity between Bronsted-Lewis acidic IL and corresponding materials (Bronsted acidic IL and metal chloride) was revealed. Meanwhile, [Ps-MTH][CF₃SO₃] and FeCl₃ are verified as the best materials for preparation of Bronsted-Lewis acidic IL, and [Ps-MTH][CF₃SO₃]-FeCl₃(x = 0.65) is determined as the most efficient catalyst in the end. The Lewis acidity, Bronsted acidity and interaction of [Ps-MTH][CF₃SO₃] and FeCl₃ in [Ps-MTH][CF₃SO₃]-FeCl₃(x = 0.65) were characterized by FT-IR. And the catalytic mechanism of transesterification catalyzed by prepared IL was clarified. In order to maximize the biodiesel yield, optimization of process variables was conducted using Box-Behnken response surface methodol. The 97.04% of high biodiesel yield is obtained under the optimum conditions: reaction temperature was 127 °C, molar ratio (methanol to soapberry oil) was 27.96:1, catalyst amount was 3.06 mmol and reaction time was 8 h. Furthermore, [Ps-MTH][CF₃SO₃]-FeCl₃(x = 0.65) presents good catalytic activity in different transesterification for biodiesel production And its catalytic activity decreases from 97.04% to 93.59% after being used for 5 times, which reflects good reusability. The main properties of soapberry biodiesel were also measured and compared to the ASTM D6751 standard

Energy Conversion and Management published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Related Products of pyrazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Dong, Dawei published the artcileCrosslinked anion exchange membranes with regional intensive ion clusters prepared from quaternized branched polyethyleneimine/quaternized polysulfone, Product Details of C4H6N2, the publication is International Journal of Hydrogen Energy (2022), 47(59), 24991-25006, database is CAplus.

A series of anion exchange membranes (AEMs) with regionally dense ion clusters are prepared by crosslinking quaternized polysulfone (QPSU) with quaternized branched polyethyleneimine (QBPEI). For the as-prepared QPSU/QBPEI AEMs, the hydrophilic QBPEI forms locally aggregated ion clusters in the QPSU matrix, which can promote the formation of an obvious microphase separation structure in the membrane. The QPSU/QBPEI-3 AEM with an ion exchange capacity of 1.88 meq/g exhibits the best performance, achieving a reasonably high ionic conductivity of 66.14 mS/cm at 80°C and showing good oxidation stability and alkali resistance. Finally, the maximum power d. of a single H₂/O₂ fuel cell with QPSU/QBPEI-3 AEM reaches 75.34 mW/cm² at 80°C. The above results indicate that QBPEI with a dendritic structure and abundant anionic conductive groups has a good application prospect in the preparation of AEMs with locally aggregated ion clusters and microphase separation structures.

International Journal of Hydrogen Energy published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Product Details of C4H6N2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Zhang, Qingwei published the artcileHit to Lead optimization of a novel class of squarate-containing polo-like kinase inhibitors, COA of Formula: C3H5BN2O2, the publication is Bioorganic & Medicinal Chemistry Letters (2012), 22(24), 7615-7622, database is CAplus and MEDLINE.

Aminodioxocyclobutenylamino pyrimidineamines (aminopyrimidine squaramides) such as I, derived from a squaramide identified through high-throughput screening, were prepared as selective Polo-like kinase 1 (Plk1) inhibitors for potential use as antitumor agents. Using mol. modeling and extensive structure-activity studies, I (Plk1 K_i = 5 nM; EC₅₀ = 1.05 μM) was identified; its inhibition of Plk1 and of a panel of kinases, its lipophilicity, and its pharmacokinetics were determined I demonstrated moderate efficacy at dosages of 100 mg/kg in a murine pancreatic cancer xenograft tumor model and no overt toxicity.

Bioorganic & Medicinal Chemistry Letters published new progress about 763120-58-7. 763120-58-7 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Boronic acid and ester,Boronic Acids,Boronic acid and ester, name is 1H-Pyrazole-4-boronic acid, and the molecular formula is C9H17NO, COA of Formula: C3H5BN2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Fillion, Joseph J. published the artcilePhase Transitions, Decomposition Temperatures, Viscosities, and Densities of Phosphonium, Ammonium, and Imidazolium Ionic Liquids with Aprotic Heterocyclic Anions, HPLC of Formula: 930-36-9, the publication is Journal of Chemical & Engineering Data (2016), 61(8), 2897-2914, database is CAplus.

Ionic liquids (ILs) with aprotic heterocyclic anions (AHAs) have been developed primarily for CO₂ capture applications. However, they have also been considered for cofluid CO₂/IL vapor compression refrigeration cycles and for various electrochem. applications. In all of these cases, reducing the viscosity of the IL is of primary importance. Therefore, the focus of this work is tuning the cation to produce AHA ILs with both low viscosities and low m.ps. Toward this goal we have synthesized 40 AHA ILs paired with phosphonium, ammonium and imidazolium cations, as well as a number of ILs with the bis(trifluoromethylsulfonyl)imide anion to use for comparison. The azolide anions investigated were 2-cyanopyrrolide, 4-nitropyrazolide, various substituted imidazolides, 1,2,3-triazolide, and tetrazolide. M.ps., glass transition temperatures, and decomposition temperatures were measured for all ILs. Viscosities and densities were measured from 278.15 to 343.15 K and 283.15 to 353.15 K, resp., for all ILs except those with high m.ps. or excessively high viscosities. Shortening the alkyl chains on tetra-alkylphosphonium and tetra-alkylammonium cations reduces viscosity, but eventually results in unacceptably higher m.ps. For equivalent alkyl chain lengths and anions, ammoniums have higher m.ps. and lower decomposition temperatures than phosphoniums. The introduction of an ether chain on a phosphonium cation lowers viscosity but reduces thermal stability. Di- and trialkylimidazolium with sufficiently low m.ps. have relatively high viscosities.

Journal of Chemical & Engineering Data published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, HPLC of Formula: 930-36-9.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Conroy, Nathan A. published the artcileA Novel Method for Tracer Concentration Plutonium(V) Solution Preparation, Synthetic Route of 4551-69-3, the publication is Analytical Chemistry (Washington, DC, United States) (2016), 88(8), 4196-4199, database is CAplus and MEDLINE.

Preparation of relatively pure low concentration Pu(V) solutions for environmental studies is nontrivial due to the complex redox chem. of Pu. Ozone gas generated by an inexpensive unit designed for household-use was used to oxidize a 2 × 10^-8 M Pu(IV) solution to predominantly Pu(VI) with some Pu(V) present. Over several days, the Pu(VI) in the solution reduced to Pu(V) without further reducing to Pu(IV). The reduction from Pu(VI) to Pu(V) could be accelerated by raising the pH of the solution, which led to an immediate conversion without substantial conversion to Pu(IV). The aqueous Pu is stable as predominately Pu(V) for greater than one month from pH 3-7; however, at circumneutral pH, a sizable fraction of Pu was lost from solution by either precipitation or sorption to the vial walls. This method provides a fast means of preparing Pu(V) solutions for tracer concentration studies without numerous extraction or cleanup steps.

Analytical Chemistry (Washington, DC, United States) published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Synthetic Route of 4551-69-3.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Yi, Rong-Nan published the artcileGreen synthesis of 4-organylselanyl-1H-pyrazoles through electrochemical cross-dehydrogenative coupling of 1H-pyrazoles and diorganyl diselenides, Application In Synthesis of 930-36-9, the publication is Tetrahedron Letters (2021), 153257, database is CAplus.

An atom-economical and efficient method for synthesizing 4-organylselanyl-1H-pyrazoles through electrochem. cross-dehydrogenation coupling of N-unsubstituted pyrazoles with diorganyl diselenides under chem. oxidant-free and mild conditions was developed. This reaction not only shows good functional-group tolerance but also has high scalability.

Tetrahedron Letters published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C15H20O6, Application In Synthesis of 930-36-9.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Yan, Xingchen published the artcileCrystal structures and theoretical calculations of two peculiar compounds derived from 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one, Product Details of C17H14N2O2, the publication is Journal of Molecular Structure (2014), 609-616, database is CAplus.

A potassium coordination polymer [K₂(PMBP)₂(H₂O)₃]_n·2nH₂O (1) was prepared by reaction of 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one (HPMBP) with potassium hydroxide. The single crystal of the supermol. C₆H₁₁NH⁺₃·PMBP^– (2) was then obtained by utilizing cyclohexylamine as the proton acceptor. It is a diketonate salt with an organic base where the PMBP^– anions are stabilized by the intermol. weak interactions (including hydrogen bonding, π-π stacking interactions and Van der Waals forces), rather than by coordination to a metal center. Geometrical parameters of the isolated PMBP^– anion were optimized through quantum chem. calculation to simulate the state without any disturbances or interactions. Comparison of geometric parameters of compound 1 with the optimized structure of PMBP^– provides an approach to study weak intermol. interactions in the crystal state. The coordination sites and the proton acceptors of hydrogen bonds predicted by theor. calculations are consistent to the exptl. results.

Journal of Molecular Structure published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C19H15NO3, Product Details of C17H14N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics