Application In Synthesis of 1-Butyl-1H-pyrazoleOn October 31, 1999 ,《Structural regularities governing sorption and gas chromatographic retention of aromatic nitrogen-containing heterocyclic compounds》 appeared in Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). The author of the article were Zhuravleva, I. L.; Kuz’menko, T. E.. The article conveys some information:
The regularities governing differences in the gas-chromatog. retention indexes of aromatic N-containing heterocyclic compounds were studied during gas-chromatog. anal. on a nonpolar capillary column. The retention indexes of pyrrole, pyrazole, imidazole, 1,2,4-triazole, oxazole, thiazole, isoxazole, pyridine, pyridazine, pyrimidine, pyrazine, and s-triazine and their alkyl derivatives depend on the number, nature, and arrangement of heteroatoms and alkyl groups in the cycles. The majority of homologous series of n-alkyl-substituted azoles and azines and n-alkylbenzenes is characterized by anomalously high differences between the retention indexes of Et and Me homologs. A scheme of calculating retention indexes of aromatic heterocyclic compounds from increments of heteroatoms was proposed. In the part of experimental materials, we found many familiar compounds, such as 1-Butyl-1H-pyrazole(cas: 52096-24-9Application In Synthesis of 1-Butyl-1H-pyrazole)
1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Application In Synthesis of 1-Butyl-1H-pyrazole
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics