Discovery of Ethyl 1H-pyrazole-3-carboxylate

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5932-27-4, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5932-27-4, name is Ethyl 1H-pyrazole-3-carboxylate, This compound has unique chemical properties. The synthetic route is as follows.

R – (+) – propylene oxide (3.65 g) and After 4-amino-benzotrifluoride ethanol solution of chloride (7.78 mL) (10 mL) was stirred for 4 hours at room temperature, lithium bromide (1.64 g), R – (+) – was stirred 9 days at room temperature was added propylene oxide (1.66 g). The reaction mixture was concentrated under reduced pressure, the resulting residue was purified by silica gel column chromatography (n- hexane / ethyl acetate) to give the title compound (10.5 g).

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