Vasil’eva, V. F.; Yashunskii, V. G. published the artcile< Sydnones and sydnonimines. XIII. Reaction of 3-methyl- and 3-ethylsydnones with methyl acrylate>, HPLC of Formula: 17827-61-1, the main research area is .
Treatment of N-methylglycine with NaNO2 in aqueous HCl at 0°, followed by keeping the crude N-nitroso derivative with Ac2O 10 days at room temperature, gave 56.2% 3-methylsydnone (I), b0.7 162-5°. Similarly was prepared N-nitroso-N-ethylglycine, m. 85-6°, which with Ac2O gave 45.5% 3-ethylsydnone (II), b0.5 153-6°. Heating I with CH2:CHCO2Me 36 hrs. at 125-50° gave 56.5% Me 1-methyl-δ2-pyrazoline-3-carboxylate (III), b7 103-4°, d20 1.1162, n20D 1.5093, λ 306 mμ, and 24% crude Me x-carbomethoxy-1-methylpyrazoline-propionate (IV) (positions of attached groups not certain), b0.6 138-41°. The former in 2 days in MeOH-NH8 gave 1-methyl-δ2-pyrazolinecarboxamide, m. 116-18°, λ 296 mμ, while the latter ester gave the corresponding diamide, decomposed 241-2°. III and Pb(OAc)4 in AcOH (exothermic) gave 65% Me 1-methyl-pyrazole-3-carboxylate, b1 108-10°, which with MeOH-NH3 gave the corresponding amide, m. 139-40.5°, λ 220 mμ. 1-Methylpyrazole-4-carboxylic acid refluxed with MeOH-H2SO4 in C5H6 gave the Me ester, m. 63-4.5°, which with MeOH-NH3 1 day in a sealed tube gave the amide, m. 181.5-83°. II and CH2:CHCO2Me in 34 hrs. at 125° gave 51% Me 1-ethyl-δ2-pyrazoline-3-carboxylate (V), b7 110-12° b0.8 90° 1.0860, 1.5065, and some 25% crude 1-ethyl analog of IV, b0.5 135-42°. The former in MeOH-NH3 gave the amide, m. 92-4° while the latter ester similarly gave the diamide, decomposed 251-2°. V and Pb(OAc)4, as above, gave 62.5% Me 1-ethylpyrazole-3-carboxylate, b6 115-16°, which gave the amide, m. 100-1°. Infrared and ultraviolet spectra of the esters are reported.
Zhurnal Obshchei Khimii published new progress about IR spectra. 17827-61-1 belongs to class pyrazoles-derivatives, and the molecular formula is C6H8N2O2, HPLC of Formula: 17827-61-1.
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics