Synthetic Route of C9H9NO. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about A new facile chemoenzymatic synthesis of levamisole.
An efficient and facile chemoenzymic synthesis of levamisole by employing lipase-mediated resolution of 3-hydroxy-3-(phenyl)propanenitrile followed by its conversion to β-amino alc. as the key intermediate is described. The resolution of β-(acetyloxy)benzenepropanenitrile using diatomite-immobilized Pseudomonas cepacia (Burkholderia cepacia) lipase gave (+)-(βR)-β-(hydroxy)benzenepropanenitrile. The resolution of β-(hydroxy)benzenepropanenitrile using immobilized lipase gave (βR)-β-(acetyloxy)benzenepropanenitrile. Both intermediates were used for the synthesis of (6S)-2,3,5,6-tetrahydro-6-(phenyl)imidazo[2,1-b]thiazole (levamisole).
Different reactions of this compound(3-Hydroxy-3-phenylpropanenitrile)Synthetic Route of C9H9NO require different conditions, so the reaction conditions are very important.
Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics