Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Chemistry – An Asian Journal called Sequential SNAr Reaction/Suzuki-Miyaura Coupling/C-H Direct Arylations Approach for the Rapid Synthesis of Tetraaryl-Substituted Pyrazoles, Author is Morita, Taiki; Kobayashi, Daisuke; Matsumura, Keisuke; Johmoto, Kohei; Uekusa, Hidehiro; Fuse, Shinichiro; Takahashi, Takashi, which mentions a compound: 52287-51-1, SMILESS is BrC1=CC=C2OCCOC2=C1, Molecular C8H7BrO2, Category: pyrazoles-derivatives.
The rapid synthesis of 1,3,4,5-tetraaryl-substituted pyrazoles I (R1 = CN, NO2; R2 = 4-CF3, 4-MeO, 2-Me; R3 = CN, Me, CO2Et; R4 = 4-O2NC6H4, naphthalen-2-yl, 2,3-dihydro-1,4-benzodioxin-6-yl, etc.) was achieved through a sequence of SNAr reaction/Suzuki-Miyaura coupling/Pd-catalyzed direct arylations that used 3-iodo-1H-pyrazole as a scaffold. Compounds I were synthesized in a straightforward manner with no extra synthetic steps, such as protection/deprotection or the introduction of activating/directing groups, using readily available substrates and reagents. The developed synthetic approach enabled the structurally diverse synthesis of multiaryl-substituted pyrazoles without using glovebox techniques.
The article 《Sequential SNAr Reaction/Suzuki-Miyaura Coupling/C-H Direct Arylations Approach for the Rapid Synthesis of Tetraaryl-Substituted Pyrazoles》 also mentions many details about this compound(52287-51-1)Category: pyrazoles-derivatives, you can pay attention to it or contacet with the author([email protected]; [email protected]) to get more information.
Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics