Application of 17190-29-3. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about Synthetic application of cyanoaminosilanes as azomethine ylide equivalents. Author is Padwa, Albert; Chen, Yon Yih; Dent, William; Nimmesgern, Hildegard.
A series of α-cyanoaminosilanes acted as azomethine ylide equivalent Treatment of these compounds with AgF in the presence of electron-deficient alkynes and olefins gives substituted pyrroles and pyrrolidines in high yield. Me3SiCH2N(CH2Ph)CH2CN (I) undergoes stereospecific cycloaddition with di-Me fumarate and maleate. The stereospecificity of the reaction is consistent with a concerted cycloaddition reaction. The cycloaddition behavior of an unsym. substituted α-cyanosilylamine with MeO2CCCH was also examined and found to react with high overall regioselectivity. The synthetic utility of cyanoaminosilanes as azomethine ylide equivalent was demonstrated by the preparation of a Reniera isoindole alkaloid (II). The key step in the synthesis involved the reaction of 2-methyl-3-methoxyquinone with I in the presence of AgF to give 2,5-dimethyl-6-methoxyisoindole-4,7-dione in good yield.
After consulting a lot of data, we found that this compound(17190-29-3)Application of 17190-29-3 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics