So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Cheng, Chen; Hartwig, John F. researched the compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5 ).Related Products of 1300746-79-5.They published the article 《Rhodium-Catalyzed Intermolecular C-H Silylation of Arenes with High Steric Regiocontrol》 about this compound( cas:1300746-79-5 ) in Science (Washington, DC, United States). Keywords: rhodium catalyzed intermol carbon hydrogen silylation arene steric regiocontrol. We’ll tell you more about this compound (cas:1300746-79-5).
Regioselective C-H functionalization of arenes has widespread applications in synthetic chem. The regioselectivity of these reactions is often controlled by directing groups or steric hindrance ortho to a potential reaction site. Here, authors report a catalytic intermol. C-H silylation of unactivated arenes that manifests very high regioselectivity through steric effects of substituents meta to a potential site of reactivity. The silyl moiety can be further functionalized under mild conditions but is also inert toward many common organic transformations, rendering the silylarene products useful building blocks. The remote steric effect that we observe results from the steric properties of both the rhodium catalyst and the silane.
Although many compounds look similar to this compound(1300746-79-5)Related Products of 1300746-79-5, numerous studies have shown that this compound(SMILES:F[C-](F)([Cu+]1[N]2=C3C4=[N]1C=CC=C4C=CC3=CC=C2)F), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics