Itoh, Toshiyuki; Takagi, Yumiko; Nishiyama, Shigenori published the article 《Enhanced enantioselectivity of an enzymatic reaction by the sulfur functional group. A simple preparation of optically active β-hydroxy nitriles using a lipase》. Keywords: methylthioacetoxybutyronitrile kinetic resolution lipase; nitrile beta hydroxy optically active.They researched the compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ).Computed Properties of C9H9NO. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:17190-29-3) here.
The enantioselectivity of a lipase-catalyzed hydrolysis was improved by varying the acyl residue into the sulfur functional one, i.e. the β-(phenylthio)- or β-(methylthio)acetoxy group, from acetate or valerate to realize satisfactory resolution of β-hydroxy nitriles using lipase P (Pseudomons sp.).
Although many compounds look similar to this compound(17190-29-3)Computed Properties of C9H9NO, numerous studies have shown that this compound(SMILES:N#CCC(O)C1=CC=CC=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics