Takahashi, Kazumasa; Sasaki, Kazushige; Tanabe, Hiroaki; Yamada, Kazutoshi; Iida, Hirotada published an article about the compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3,SMILESS:N#CCC(O)C1=CC=CC=C1 ).Recommanded Product: 3-Hydroxy-3-phenylpropanenitrile. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:17190-29-3) through the article.
The reaction of MeCN with p-anisaldehyde was studied in detail. In EtOH no reaction occurred, but in DMF, (Me2N)3PO or THF the reaction rapidly proceeded to give 2-cyano-1-(4-methoxyphenyl)-1-hydroxyethane (I) and 4-methoxycinnamonitrile (II) with total yield of 87 ∼ 95%. The yields of I and II were influenced by the reaction temperature and solvent. Prolonged treatment of MeCN with RC6H4CHO(R = H, p-MeO, p-Me2N), 2,4-(MeO)2-C6H3CHO or 3,4-(methylenedioxy)benzaldehyde under similar conditions gave β-hydroxy-β-phenylpropionitrile derivatives or cinnamonitrile derivatives Their yields were influenced by the substituents.
Although many compounds look similar to this compound(17190-29-3)Recommanded Product: 3-Hydroxy-3-phenylpropanenitrile, numerous studies have shown that this compound(SMILES:N#CCC(O)C1=CC=CC=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics