Introduction of a new synthetic route about 17190-29-3

Compounds in my other articles are similar to this one(3-Hydroxy-3-phenylpropanenitrile)Recommanded Product: 3-Hydroxy-3-phenylpropanenitrile, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about One-Pot Nitrile Aldolization/Hydration Operation Giving β-Hydroxy Carboxamides.Recommanded Product: 3-Hydroxy-3-phenylpropanenitrile.

A straightforward method to provide 3-hydroxy carboxamides from aldehydes, nitriles, and water is reported. The method is atom-economical and redox neutral. The present reaction is essentially the first example of the catalytic aldol reaction of “”unactivated”” carboxamides (CONH2). No protection/activation/deprotection sequence is needed and thus the formation of a stoichiometric amount of salt waste is obviated.

Compounds in my other articles are similar to this one(3-Hydroxy-3-phenylpropanenitrile)Recommanded Product: 3-Hydroxy-3-phenylpropanenitrile, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics