Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 17190-29-3, is researched, Molecular C9H9NO, about Ring opening of 3-bromo-2-isoxazolines to β-hydroxy nitriles, the main research direction is bromoisoxazoline ring opening; ring opening reaction mechanism; hydroxy nitrile preparation.Safety of 3-Hydroxy-3-phenylpropanenitrile.
3-Bromo-2-isoxazolines were converted to the corresponding β-hydroxy nitriles by treatment with sodium iodide in the presence of either chlorotrimethylsilane or p-toluenesulfonic acid. Both methods gave β-hydroxy nitriles under relatively mild conditions in good to moderate yields for a variety of substituted 3-bromo-2-isoxazolines.
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Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics