Related Products of 52287-51-1. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine, is researched, Molecular C8H7BrO2, CAS is 52287-51-1, about Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes. Author is Cheng, Xinyi; Liu, Xingchen; Wang, Shengchun; Hu, Ying; Hu, Binjing; Lei, Aiwen; Li, Jie.
A cobalt-catalyzed regioselective difluoroalkylarylation of both activated and unactivated alkenes with solid arylzinc pivalates and difluoroalkyl bromides through a cascade Csp3-Csp3/Csp3-Csp2 bond formation under mild reaction conditions. Indeed, a wide range of functional groups on difluoroalkyl bromides, olefins, 1,3-dienes as well as (hetero)arylzinc pivalates are well tolerated by the cobalt-catalyst, thus furnished three-component coupling products in good yields and with high regio- and diastereoselectivity. Kinetic experiments compared arylzinc pivalates and conventional arylzinc halides highlighted the unique reactivity of these organozinc pivalates. Mechanistic studies strongly supported that the reaction involved direct halogen atom abstraction via single electron transfer to difluoroalkyl bromides from the in-situ formed cobalt(I) species, thus realized a Co(I)/Co(II)/Co(III) catalytic cycle.
In addition to the literature in the link below, there is a lot of literature about this compound(6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine)Related Products of 52287-51-1, illustrating the importance and wide applicability of this compound(52287-51-1).
Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics