Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 17190-29-3, is researched, Molecular C9H9NO, about A cobalt-phosphine complex as mediator in the formation of carbon-carbon bonds, the main research direction is cobalt phosphine catalyst carbon bond formation; carbonyl addition halocarbon cobalt catalyst.Safety of 3-Hydroxy-3-phenylpropanenitrile.
Co(PMe3)4, either preformed or prepared in situ by reduction of 1:4 CoCl2 and Me3P with Mg metal in THF, is an efficient mediator for the reaction of carbonyl compounds R1R2CO with activated halocarbons XCR3R4COR5 to give alcs. HOCR1R2CR3R4COR5 (R1 = alkyl, alkenyl, aryl; R2, R3, R4 = H, alkyl; R5 = OMe, OEt, OBu-t, NEt2; R4R5 = CH2CH2O; X = Cl, Br). The reaction proceeds with good yields under very mild conditions and can be carried out in a 1-pot procedure with only a catalytic amount of Co(PMe3)4, provided sufficient Mg metal is also present.
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Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics