Kumagai, Naoya; Matsunaga, Shigeki; Shibasaki, Masakatsu published the article 《Cooperative catalysis of a cationic ruthenium complex, amine base, and Na salt: catalytic activation of acetonitrile as a nucleophile》. Keywords: aldehyde acetonitrile addition ruthenium DBU sodium fluorophosphate; aryl hydroxypropanenitrile preparation; aminopropanenitrile preparation; ruthenium DBU sodium fluorophosphate addition catalyst.They researched the compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ).Formula: C9H9NO. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:17190-29-3) here.
Cooperative catalysis of a cationic Ru complex, DBU, and NaPF6 is described. An exquisite combination of the catalytic triad enabled catalytic activation of acetonitrile as a nucleophile under mild amine-basic conditions. Addition of in situ-generated, Ru-bound, metalated nitrile to aldehydes and imines proceeded smoothly with catalytic amounts of Ru complex and DBU in the presence of a catalytic amount of NaPF6. Preliminary mechanistic studies suggested a role for each of the three catalytic components.
This literature about this compound(17190-29-3)Formula: C9H9NOhas given us a lot of inspiration, and I hope that the research on this compound(3-Hydroxy-3-phenylpropanenitrile) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics