So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Dauksas, V.; Gaidelis, P.; Brukstus, A.; Petrauskas, O.; Udrenaite, E.; Gasperaviciene, G. researched the compound: 6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine( cas:52287-51-1 ).Quality Control of 6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine.They published the article 《Synthesis and antiinflammatory activity of 7-halo- (or -ethyl-)substituted 6-benzoyl- (or -cinnamoyl)-1,4-benzodioxanes》 about this compound( cas:52287-51-1 ) in Chemija. Keywords: acylation benzodioxane halo ethyl; benzoylbenzodioxane preparation antiinflammatory; cinnamoylbenzodioxane preparation antiinflammatory; antiinflammatory cinnamoylbenzodioxane benzoylbenzodioxane. We’ll tell you more about this compound (cas:52287-51-1).
Title compounds I (R = PhCO, PhCH:CHCO; X = Br, Cl, Et) were synthesized in 72-95% yield by acylating I (R = H; same X) with BzCl or PhCH:CHCOCl in the presence of anhydrous AlCl3. I (R = PhCO, X = Br) exhibits low toxicity and high antiinflammatory activity; other products are less active.
Compound(52287-51-1)Quality Control of 6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine), if you are interested, you can check out my other related articles.
Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics