So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Zhang, Hao-Ran; Xiao, Chang; Zhang, Song-Lin; Zhang, Xiaoming researched the compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5 ).Application of 1300746-79-5.They published the article 《Radical C-H Bond Trifluoromethylation of Alkenes by High-Valent Copper(III) Trifluoromethyl Compounds》 about this compound( cas:1300746-79-5 ) in Advanced Synthesis & Catalysis. Keywords: diarylalkene copper trifluoromethyl complex trifluoromethylation; alkene trifluoromethyl preparation. We’ll tell you more about this compound (cas:1300746-79-5).
A general and selective method is developed that allows direct vinylic C-H bond trifluoromethylation of 1,1-diarylalkenes 4-R1C6H5C(Ar1)=CH2 (R = H, Me, F, CN, etc.; Ar1 = Ph, 3,4-dimethylphenyl, thiophen-2-yl, etc.) and 2-methylidenetricyclo[9.4.0.0(3,8)]pentadeca-1(11),3,5,7,12,14-hexaene by a high-valent copper(III) trifluoromethyl complex, R2Cu(CF3)3 (R2 = 1,10-phenanthroline, pyridine) producing biol. active trifluoromethylated alkenes (as well as trifluoromethylated carbocyclic compounds) (E/Z)-4-R1C6H5C(Ar1)=CHCF3 and 5-(2,2,2-trifluoroethylidene)-10,11-dihydro-5H-dibenzo[a,d][7]annulene. This fundamental reactivity of Cu(III)-CF3 compounds has thus far been unknown. The presence of a tertiary amine is crucial to this reaction, acting as both a weak base and a single electron transfer (SET) promoter to abstract the vinylic hydrogen. This method starts from bulk olefins under cost-effective conditions (without the need for external noble metal photocatalyst or stoichiometric amounts of oxidant), and thus is valuable for practical and sustainable applications.
There is still a lot of research devoted to this compound(SMILES:F[C-](F)([Cu+]1[N]2=C3C4=[N]1C=CC=C4C=CC3=CC=C2)F)Application of 1300746-79-5, and with the development of science, more effects of this compound(1300746-79-5) can be discovered.
Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics