What unique challenges do researchers face in 3-Methyl-1-p-tolyl-5-pyrazolone

Application In Synthesis of 3-Methyl-1-p-tolyl-5-pyrazolone. Welcome to talk about 86-92-0, If you have any questions, you can contact Lu, H; Zhang, HX; Tan, CY; Liu, JY; Wei, H; Xu, PF or send Email.

Recently I am researching about N-HETEROCYCLIC CARBENE; ENANTIOSELECTIVE CONSTRUCTION; ORGANOCATALYSIS; PYRAZOLONES; ANNULATION; SCAFFOLDS; OXINDOLES; CATALYSIS, Saw an article supported by the NSFCNational Natural Science Foundation of China (NSFC) [21632003, 21871116, 21572087]; key program of Gansu province [17ZD2GC011]; 111 program from the MOE of P. R. China. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Lu, H; Zhang, HX; Tan, CY; Liu, JY; Wei, H; Xu, PF. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone. Application In Synthesis of 3-Methyl-1-p-tolyl-5-pyrazolone

A sequential and general strategy has been successfully developed for the synthesis of spiropyrazolone scaffolds. This intriguing transformation of the asymmetric multicomponent catalysis process was realized with the combination of Michael addition/chlorination/nucleophilic substitution in a one-pot sequence, giving rise to a series of spiropyrazolones with fully substituted cyclopropanes and spiro-dihydrobenzofurans containing continuous stereogenic centers in good yields with excellent stereoselectivities.

Application In Synthesis of 3-Methyl-1-p-tolyl-5-pyrazolone. Welcome to talk about 86-92-0, If you have any questions, you can contact Lu, H; Zhang, HX; Tan, CY; Liu, JY; Wei, H; Xu, PF or send Email.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics