14521-80-3, Adding some certain compound to certain chemical reactions, such as: 14521-80-3, name is 3-Bromo-1H-pyrazole, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 14521-80-3.
General procedure: To a solution of pyrazole 1-5 (1 equiv.) and triethylamine (1.5 equiv.) in dichloromethane (for 0.05mol of pyrazole – 50 mL of dichloromethane were user) Di-tert-butyl dicarbonate (1.2 equiv) wereadded at room temperature and left to stir overnight. Dichloromethane was washed with saturatedNaHCO3 solution (1¡Á25 mL – for 50 mL of dichloromethane) then with deionized H2O (1 ¡Á 25mL). Organic layer was dried with anhydrous Na2SO4, and evaporated under reduced pressure.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 14521-80-3.