89501-90-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 89501-90-6, name is 1-Methyl-1H-pyrazole-3-sulfonyl chloride belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
General procedure: A solution of sulfonyl chloride (1 eq) in THE (10-20 mL/mmol) was cooled to-78C and ammonia gas was bubbled through the solution for 15 mm, stirring was continued for a further 30 mm then allowed to warm to ambient temperature and stirred for 2h or until completion. The sulfonyl chloride was converted using general method E1 to give the titled compound as an off-white solid (0.4 g, 69%). 1 H NMR (400 MHz, DMSO-d6): delta = 7.80 (d, J = 2.1 Hz, 1 H), 7.36 (s, 2H), 6.53 (d, J = 2.1 Hz, 1 H), 3.88 (s, 3H). LCMS (m/z): 162.05 (M +1 )+.
The synthetic route of 89501-90-6 has been constantly updated, and we look forward to future research findings.