In 2020.0 J ORG CHEM published article about O-GLYCOSYLATION; AMIDE; REARRANGEMENT; CONSTRUCTION; GLYCOPROTEIN; INHIBITOR; DESIGN; CANCER in [Wang, Ying; Yao, Hui; Hua, Min; Jiao, Yang; He, Haibo; Liu, Mingguo; Huang, Nianyu; Zou, Kun] China Three Gorges Univ, Coll Biol & Pharmaceut Sci, Hubei Key Lab Nat Prod Res & Dev, Yichang 443002, Peoples R China in 2020.0, Cited 36.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Safety of 3,5-Dimethyl-1H-pyrazole
Direct N-glycosylation between glycals and amides/amines was achieved with exclusive stereoselectivity in moderate to high yields. Various amides, amines, and 3,4-O-carbonate-glycals were tolerated, and unique beta-N-glycosides were obtained. The strategy was based on palladium-catalyzed decarboxylative allylation, and the high 1,4-cis-selectivity was proposed because of the hydrogen bonding effect. Notably, all the synthesized products were subjected to preliminary bioactivity studies, revealing that three compounds were cytotoxic to tumor cells and nontoxic to normal human cells.
Welcome to talk about 67-51-6, If you have any questions, you can contact Wang, Y; Yao, H; Hua, M; Jiao, Y; He, HB; Liu, MG; Huang, NY; Zou, K or send Email.. Safety of 3,5-Dimethyl-1H-pyrazole
Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics