COA of Formula: C5H8N2. I found the field of Chemistry very interesting. Saw the article The development of a Cu(I)/pyrazolylpyridineamine catalyst system for the hydroxylation of aryl halides published in 2020.0, Reprint Addresses Swarts, AJ (corresponding author), North West Univ, Focus Area Chem Resource Beneficiat, Catalysis & Synth Res Grp, 11 Hoffman St, ZA-2520 Potchefstroom, South Africa.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole.
A catalyst system comprising of pyrazolylpyridineamine/Cu(I)/CsOH is reported. for the hydroxylation of aryl iodides and bromides with moderate to outstanding yields, without the use of an inert atmosphere. A comprehensive parameter optimisation study established optimum component concentrations: [Cu(MeCN)(4)]BF4 and 2-(1H-pyrazol-1-yl)-N-(pyridine-2-ylmethyl)ethan-1-amine (L01) (2 mol %), substrate (1 mmol), CsOH (4 mmol) and DMSO:H2O (1:1, 3 mL). Monitoring substrate conversion as a function of time revealed an induction period of 90 min, which could be eliminated through the initial in situ formation of the proposed [(L01)Cu-OH] intermediate. Eliminating the induction period resulted in complete conversion within one hour, with turnover numbers exceeding that of the benchmark catalyst system operating at an optimal catalyst loading of 0.05 mol %.
COA of Formula: C5H8N2. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Marais, L; Vosloo, HCM; Swarts, AJ or concate me.
Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics