Simple exploration of 3-Amino-5-(methylthio)-1H-pyrazole-4-carbonitrile

The chemical industry reduces the impact on the environment during synthesis 3-Amino-5-(methylthio)-1H-pyrazole-4-carbonitrile. I believe this compound will play a more active role in future production and life.

Reference of 72760-85-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 72760-85-1, name is 3-Amino-5-(methylthio)-1H-pyrazole-4-carbonitrile, This compound has unique chemical properties. The synthetic route is as follows.

General procedure: A mixture of pyrazole-imines 7 (1 mmol), aldehyde (1 mmol), TMSCN (1.2 mmol) in [Bmim]BF4 (0.5 g) was heated at 120 C for 24 h. After cooling, the reaction mixture was washed with water (5 mL) and the residue washed with MeOH to afford pure product 8.

The chemical industry reduces the impact on the environment during synthesis 3-Amino-5-(methylthio)-1H-pyrazole-4-carbonitrile. I believe this compound will play a more active role in future production and life.

Reference:
Article; Goli, Shokoufe; Mirzaei, Peiman; Bazgir, Ayoob; Journal of the Iranian Chemical Society; vol. 15; 12; (2018); p. 2803 – 2809;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics