Adding a certain compound to certain chemical reactions, such as: 27258-32-8, name is 1-Methyl-1H-pyrazole-3-carbaldehyde, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 27258-32-8, Recommanded Product: 1-Methyl-1H-pyrazole-3-carbaldehyde
in room temperature, Mix 1-methyl-1H-pyrazole-3-carbaldehyde (11.0 g, 0.1 mol), sodium bromate (4.5 g, 0.03 mol) and 100 g of acetic acid (1.67 mol), add 25 g of ammonia-containing molecular mass concentration 25percent ammonia water and 400 ml water, heated to 90 ° C, the reaction exotherm, maintain the reaction temperature 100 ° C, reflux reaction for 1 hour until 1-methyl-1H-pyrazole-3-carbaldehyde reaction is complete, the reaction solution is cooled to room temperature Pour into ice water to quench and dilute, neutralize until the reaction solution is neutral, extract with ethyl acetate, dry, concentrate the product, distill it under reduced pressure and recrystallize to obtain 8.6 g of product, yield 80percent, purity 98percent the above.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Methyl-1H-pyrazole-3-carbaldehyde, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Changsha Luxing Biological Technology Co., Ltd.; Tan Yongjun; (14 pag.)CN108707113; (2018); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics