Some common heterocyclic compound, 59843-75-3, name is 3-(p-Tolyl)-1H-pyrazole, molecular formula is C10H10N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Product Details of 59843-75-3
Production Example 143 3-p-Tolyl-1-trityl-1H-pyrazole 6.94 g of the title compound was obtained as pale brown crystals from 4.59 g 3-p-tolyl-1H-pyrazole (compound in Production Example 126) by the same method as in Production Example 15.1H-NMR (CDCl3) delta: 2.35(s, 3H), 6.50(d, J=2.4Hz, 1H), 7.16(d, J=8.0Hz, 2H), 7.21(m, 6H), 7.27 (d, J=2. 4Hz, 1H), 7.30(m, 9H), 7.69(d, J=8.0Hz, 2H)
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 59843-75-3, its application will become more common.
Reference:
Patent; Eisai Co., Ltd.; EP1382603; (2004); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics