Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 943541-20-6, name is 3-Chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazine, This compound has unique chemical properties. The synthetic route is as follows., SDS of cas: 943541-20-6
Quinazolin-6-yl-acetic acid hydrazide (0.032 g, 0.158 mmol) and 3-chloro-6-(l- methyl-lH-pyrazol-4-yl)-pyridazine (0.031 g, 0.158 mmol) were heated to 165C in 5 butanol (2 mL) for five hours. The reaction was cooled to room temperature, evaporated in vacuo and purified via silica gel column chromatography eluting with 5% methanol in dichloromethane to give 0.0031g (7%) of 6-[6-( 1 -methyl- IH- pyrazol^-yO-tl^^triazolo^.S-blpyridazin-S-ylmethyll-quinazoline. 1H NMR (400 MHz, CD3OD) 5 8.45 (s, IH), 8.29 (s, IH), 8.06 (d, 2H, J=9.6Hz), 7.60 (d, 2H,
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 943541-20-6.
Reference:
Patent; JANSSEN PHARMACEUTICA, N.V.; WO2007/75567; (2007); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics