Adding a certain compound to certain chemical reactions, such as: 57012-20-1, name is (1,3-Dimethyl-1H-pyrazol-5-yl)methanol, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 57012-20-1, Quality Control of (1,3-Dimethyl-1H-pyrazol-5-yl)methanol
To a stirring solution of (2,5-dimethyl-2H-pyrazol-3-yl)-methanol (100 mg, 0.79 mmol) in diethyl ether (3 ml.) is added PBr3 (25 //L, 0.26 mmol). The reaction is stirred at room temperature for 18 hours, then water is added. The diethyl ether layer is separated and stored over solid NaOH and used in Step 71b without further characterization.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (1,3-Dimethyl-1H-pyrazol-5-yl)methanol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; NOVARTIS AG; NOVARTIS PHARMA GMBH; WO2007/68418; (2007); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics