Discovery of 3,5-Dimethyl-4-iodopyrazole

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,5-Dimethyl-4-iodopyrazole, other downstream synthetic routes, hurry up and to see.

Adding a certain compound to certain chemical reactions, such as: 2033-45-6, name is 3,5-Dimethyl-4-iodopyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2033-45-6, Product Details of 2033-45-6

In a 50 ml reaction vessel under argon, a solution of crude 4-iodo-3,5-dimethyl-1 H- pyrazole x52 (1.15 g, 5.2 mmol) in 25 ml of dry CH2CI2 is added to 4- methylbenzenesulfonyl chloride (1.18 g, 6.2 mmol). Pyridine (0.42 ml, 5.2 mmol) is added EPO and the mixture is stirred for 16 h at room temperature. The organic phase is washed with water, dried over MgSOphi filtered and concentrated. The residue is purified by column chromatography on silicagel (Ch^C^/hexane: 70/30 (v/v)) to afford 4-iodo-3,5-dimethyl-1- [(4-methylphenyl)sulfonyl]-1H-pyrazole x53 (1.44 g).Yield : 74 %.LC-MS (MH+): 377.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,5-Dimethyl-4-iodopyrazole, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; UCB S.A.; WO2006/128692; (2006); A2;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics