Synthetic Route of 876343-24-7,Some common heterocyclic compound, 876343-24-7, name is 1-Ethyl-1H-pyrazol-4-amine, molecular formula is C5H9N3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
[2]; 2-(6-Chlorobenzotriazol- 1 -yl)- 1 , 1 ,3,3-tetramethyluronium tetrafluoroborate was used in place of 2-(7-azabenzotriazol-l-yl)-l,l53,3-tetramethyluronium hexafluorophosphate(V) as the coupling agent. The product gave the following characterising data :- 1H NMR Spectrum: (DMSOd6) 1.32 (t, 3H), 3.61 (s, 2H), 3.77 (s, 3H), 4.07 (q, 2H), 6.76 (d, IH), 6.92 (m, IH), 7.06 (d, IH), 7.38 (d, IH), 7.42 (s, IH)5 7.88 (s, IH), 8.08 (s, IH), 8.92 (d, IH), 9.57 (s, IH), 10.05 (s, IH); Mass Spectrum: M+H+ 438 and 440.
The synthetic route of 876343-24-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2007/113565; (2007); A1;,
Pyrazole – Wikipedia,
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