Adding a certain compound to certain chemical reactions, such as: 143426-52-2, name is 1-(4-(Chloromethyl)phenyl)-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 143426-52-2, name: 1-(4-(Chloromethyl)phenyl)-1H-pyrazole
4 g of the compound was dissolved in 30 mL of acetone, followed by the addition of 12 mmol of sodium acetate. To the solution was added thereto at room temperature, 6 mmol was added, and the reaction was refluxed for 13 hours.The resulting residue was purified by columnchromatography to obtain the title compound Ig
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1-(4-(Chloromethyl)phenyl)-1H-pyrazole, and friends who are interested can also refer to it.
Reference:
Patent; Nantong University; Dai Hong; Shi Yujun; Yao Wei; Song Chan; Qian Hongwei; Wang Xianglong; Zhang Zhou; Han Xudong; (16 pag.)CN106946782; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics