Related Products of 57999-06-1, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 57999-06-1 name is 4-Phenyl-1H-pyrazol-5-amine, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
The final product 03 (24.4 mg, 0.075 mmol), 4-phenyl-1H-pyrazole-5-amine (36 mg, 0.226 mmol) and Et3N (30 mg, 0.3 mmol) were weighed into a bottle,Add 2 mL of DMF to dissolve the reaction reagent.The reaction was heated at 50 C overnight.The crude reaction product was directly purified by reversed-phase HPLCThe target compound YC008 (22 mg) was obtained.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 4-Phenyl-1H-pyrazol-5-amine, and friends who are interested can also refer to it.
Reference:
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Zhao Yujun; Li Jia; Wang Zengtao; Zhang Shiyan; Zang Yi; Wang Peipei; Sun Dandan; Zhang Hanyan; (155 pag.)CN110818683; (2020); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics