Related Products of 1572-10-7, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 1572-10-7 as follows.
General procedure: An oven dried 25 mL RB flaskwas charged with chalcone (1.0 mmol), 3-aminopyrazole (1.2 mmol), KOH (0.1mmol) and DMF (5 mL). The resulting solution was stirred at 110 C for 20 min.On completion, the reaction mass was allowed to cool to ambient temperature,diluted with water (20 mL) and extracted into ethyl acetate (2 20 mL). The combined organic layers were dried overanhydrous Na2SO4, and organic solvent was evaporated on arotatory evaporator. The crude residue was purified by column chromatography(silica gel 60-120 mesh, eluent 20% EtOAc/hexanes).
According to the analysis of related databases, 1572-10-7, the application of this compound in the production field has become more and more popular.
Reference:
Article; Kaswan, Pinku; Pericherla, Kasiviswanadharaju; Purohit, Deepshikha; Kumar, Anil; Tetrahedron Letters; vol. 56; 3; (2015); p. 549 – 553;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics