Related Products of 95162-14-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 95162-14-4, name is 4-Bromo-1-tritylpyrazole belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
A stirred mixture of 5.0 g (12.8 mmol) of 4-bromo-1-trityl-1H-pyrazole, 9.8 g (38.6 mmol, 3.0 eq.) of bis(pinacolato)diboron, 1.0 g (1.3 mmol, 10 mol %) of PdCl2(dppf) and 6.3 g (64.2 mmol, 5.0 eq) of potassium acetate in DMF (30 mL) was heated at 80 C. for 16 h. The resulting mixture was diluted with water, and the product was extracted with dichloromethane. The organic layer was washed with brine, dried over sodium sulfate, and purified by flash chromatography to give 5.1 g (91%) of 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-trityl-1H-pyrazole.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Bromo-1-tritylpyrazole, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Bentzien, Joerg Martin; Takahashi, Hidenori; US2008/261975; (2008); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics