Reference of 16082-33-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 16082-33-0, name is 1H-Pyrazole-3,5-diamine belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
Preparative Example 2 A mixture of the product from Preparative Example 1 (980 mg, 10.0 mmol) and ethyl benzoylacetate (2.20 g, 11.5 mmol) in AcOH (15 mL) was stirred and refluxed under N2 for 5 hr. The mixture was cooled to 25 C., the solid was filtered off, washed on filter with AcOH (20 mL), Et2O (40 mL), and dried in a vacuum. Cream-colored solid (930, 35%) was obtained. Mp>300 C. LC-MS: 269 [M+H].
The synthetic route of 1H-Pyrazole-3,5-diamine has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Schering Corporation; US2007/82902; (2007); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics