Application of 39846-84-9, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 39846-84-9, name is Ethyl 5-nitro-1H-pyrazole-3-carboxylate, This compound has unique chemical properties. The synthetic route is as follows.
To a solution of 5-Nitro-lH-pyrazole-3-carboxylic acid ethyl ester (0.925 g, 0.500 mmol) in absolute ethanol (10 cm3) was added 10% Pd/C (0.100 g). The mixture was stirred under an atmosphere of H2 at room temperature for 18 hours, filtered through Celite and the solvent removed under reduced pressure to give a green solid (0.70 g, 90%). 1H (CD3OD): 6.0 (s, IH), 4.3 (q, 2H, J=7.1, CO2CH2CH3), 1.4 (t, 3H, J=7.1,CO2CH2CH3). m/z (ES+): 156 [M+H]+
The chemical industry reduces the impact on the environment during synthesis Ethyl 5-nitro-1H-pyrazole-3-carboxylate. I believe this compound will play a more active role in future production and life.
Reference:
Patent; ARENA PHARMACEUTICALS, INC.; WO2006/127595; (2006); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics