Synthetic Route of 51395-52-9,Some common heterocyclic compound, 51395-52-9, name is 4-Bromo-3-methyl-1H-pyrazol-5(4H)-one, molecular formula is C4H5BrN2O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A mixture of 2-amino-3-quinoxalinethiol (0.177 g, 1 mmol) and the appropriate alpha-haloketones (1 mmol) in glacial acetic acid (10 mL) was heated under reflux for the appropriate time. The solvent was evaporated under reduced pressure and the precipitate was collected and recrystallised from ethanol.
The synthetic route of 51395-52-9 has been constantly updated, and we look forward to future research findings.