Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1190380-49-4, name is 1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-amine, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-amine
General procedure: [00495] A mixture of 2-chloro-N-(( 1 r,4r)-4-morpholinocyclohexyl)-5 -phenyl-7-tosyl-7H-pyrrolo [2,3 – djpyrimidin-4-amine (79 mg, 0.14 mmol, 1.0 eq), 1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-amine 9 (49mg, 0.30 mmol, 2.3 eq), and trifluoroacetic acid (0.20 mL, 2.6 mmol, 19 eq) in 2.0 mL of isopropanol was heated at 120 C in a capped vial for 4 hr. The reaction mixture was cooled to room temperature and purified on reverse phase HPLC giving N4-(( 1 r,4r)-4-morpholinocyclohexyl)-5 -phenyl-N2-( 1 -(tetrahydro-2H-pyran- 4-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-djpyrimidine-2,4-diamine as a white powder after lyophilization (1.9 mg, 2% yield). LC-MS: M+H=543.3. Also isolated 30 mg of beige solid as N4-((lr,4r)-4- morpholinocyclohexyl)-5 -phenyl-N2-(1 -(tetrahydro-2H-pyran-4-yl)- 1H-pyrazol-4-yl)-7-tosyl-7H- pyrrolo [2,3 -djpyrimidine-2,4-diamine (31% yield).
According to the analysis of related databases, 1190380-49-4, the application of this compound in the production field has become more and more popular.