Application of 31230-17-8, The chemical industry reduces the impact on the environment during synthesis 31230-17-8, name is 5-Methyl-1H-pyrazol-3-amine, I believe this compound will play a more active role in future production and life.
General procedure: In a one neck round bottom flask placed, taken 3-substituted-1H-pyrazol-5-amine (1eq) in dichloromethane and added 4N KOH (8eqin water). The reaction mixture was allowed to stir at room temperature followed by addition ofBocanhydride (1.2eq) in small batches. The reaction mixture was allowed to stir for 3h and reaction completion was monitored by thin layer chromatography (1:1 hexane: ethyl acetate). The reaction mixture was diluted in CH2Cl2, washed brine and dried with MgSO4. The crude product was purified using silica gel column chromatography.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Methyl-1H-pyrazol-3-amine, other downstream synthetic routes, hurry up and to see.