Some tips on 5-Amino-1,3-dimethylpyrazole

According to the analysis of related databases, 3524-32-1, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3524-32-1, name is 5-Amino-1,3-dimethylpyrazole, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 5-Amino-1,3-dimethylpyrazole

General procedure: A mixture of salicylaldehydes 1 (1 mmol), 4-hydroxy-6-methyl-2H-pyran-2-one 2 (1mmol) and L-proline (0.10 mmol) in EtOH (10 mL) was stirred at 80 C for 1 h. Then pyrazol-5-amines 3(1 mmol) and CuSO4 (0.20 mmol) was added to the reactor and stirred at 80 C for 4-48 h. Aftercompletion of the reaction confirmed by TLC (eluent acetone/petroleum ether (PE), V/V = 1:3), thereaction mixture was concentrated in vacuo to remove the solvent. The product purified by columnchromatography (PE-acetone = 5:1) to afford the pure product 4.

According to the analysis of related databases, 3524-32-1, the application of this compound in the production field has become more and more popular.