Application of 31230-17-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 31230-17-8, name is 5-Methyl-1H-pyrazol-3-amine belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
The 2,4-dichloroquinazoline (1.00g, 5 . 0mmol) and 5-methyl -1H-pyrazol-3-amine (498 mg, 5 . 1mmol) dissolved in ethanol (20 ml) in, adding Et3N (1.07g, 10 . 6mmol). After adding, the reaction mixture stirring at room temperature overnight, after the reaction, the reaction mixture is concentrated under reduced pressure. Added to the resulting residue in the mixed solution of water and ethanol (10/1(v/v), 22 ml), stirring beating at room temperature 0.5 hours, filtering, the filter cake is washed with petroleum ether (20mLx3) washing, collecting filter cake to obtain the title compound as light brown solid (1.30g, 100percent)
The synthetic route of 5-Methyl-1H-pyrazol-3-amine has been constantly updated, and we look forward to future research findings.