Reference of 31108-57-3, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 31108-57-3, name is 1H-Pyrazole-4-carbonitrile, This compound has unique chemical properties. The synthetic route is as follows.
Compound D (140 mg, 0.27 mmol) was dissolved in DMF (5 ml), then sodium carbonate (50 mg, 0.54 mmol), 1H-pyrazole-4-carbonitrile (57 mg, 0.54 mmol) was added, and the reaction was carried out at 25 C for 4 hours. . Pour into 1N NaOH aqueous solution (20 ml), extract EA four times (30ml x 4), wash twice with 1N hydrochloric acid (30ml x 2), Dry over anhydrous sodium sulfate, After concentration, silica gel column chromatography gave 30 mg of a colorless oily viscous liquid 2-1. The yield was 26%.
The chemical industry reduces the impact on the environment during synthesis 1H-Pyrazole-4-carbonitrile. I believe this compound will play a more active role in future production and life.