Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Recommanded Product: 645-05-6, 645-05-6, Name is Altretamine, SMILES is CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1, belongs to pyrazoles-derivatives compound. In a document, author is Biletska, Iryna M., introduce the new discover.
Chemoselective synthesis of 3-trifluoromethylpyrazole-deoxybenzoin hybrids
A simple method of the synthesis of alpha-(3(5)-trifluommethylpyrazol-5(3)-yl)-2-hydroxydeoxybenzoins by a chemoselective reaction of 2-(1,1,1-trifluoroacetonyl)chromones with hydrazine dihydrochloride was developed. This approach involves the initial attack of hydrazine at the carbonyl atom of the CF3C(O)CH2 group followed by the chromone ring opening at C-2 atom and subsequent cyclization to pyrazoles. Such synthetic strategy provides easy access to the novel type of pharmaceutically attractive 3-(trifluomethyl)pyrazole-deoxybenzoin hybrids in high yields.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 645-05-6. Recommanded Product: 645-05-6.
Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics