4233-33-4, Name is 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione, molecular formula is C8H5N3O2, belongs to pyrazoles-derivatives compound, is a common compound. In a patnet, author is Iskauskiene, Monika, once mentioned the new application about 4233-33-4, Name: 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione.
Facile synthesis of novel amino acid-like building blocks by N-alkylation of heterocyclic carboxylates with N-Boc-3-iodoazetidine
An efficient protocol providing easy access to highly functionalized heterocyclic compounds as novel organic building blocks was developed by coupling alkyl pyrazole-, indazole- and indolecarboxylates with N-Boc-3-iodoazetidine. The synthesized compounds are representatives of constrained non-chiral synthetic azole carboxylates in their N-Boc protected ester forms. Diversification of the prepared heterocyclic building blocks was achieved via application of palladium-catalyzed SuzukiMiyaura cross-coupling reactions. In total, 34 building blocks were obtained to form a highly diversified small molecule collection. The structure of the novel heterocyclic compounds was investigated and verified by advanced NMR spectroscopy methods.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 4233-33-4. The above is the message from the blog manager. Name: 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione.
Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics