One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 37622-90-5, Name is Ethyl 4-pyrazolecarboxylate, formurla is C6H8N2O2. In a document, author is Khachatryan, H. N., introducing its new discovery. SDS of cas: 37622-90-5.
Vinylacidic Acid in the Reaction of Aza-Michael with 1-Ethylpyrazole
Commercial vinylacetic acid is a mixture of isomers of but-3-enoic and but-2-enoic acids. It was shown that but-3-enoic acid undergoes isomerization in the presence of a catalytic amount of 1-ethylpyrazole. The resultingZ- andE-isomers of but-2-enoic acid enter the aza-Michael reaction with pyrazole. The(1)H NMR analysis showed that by the end of the experiment the ratio of unreactedZ- andE-isomers of but-2-enoic acid in the reaction mixture decreased by half (to 3 : 1), which pointed to a higher reactivity of theZ-isomer.
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Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics