Adding a certain compound to certain chemical reactions, such as: 2458-26-6, name is 3-Phenyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2458-26-6, COA of Formula: C9H8N2
A solution of 2,2,2-trifluoro-1- (2-iodo-phenyl) -ethanol (0.331 g, 1.1 mmol), 3-phenylpyrazole (0.144 g,(0.1 L), (1R, 2R) -N, N’-dimethyl-cyclohexane-1,2-diamine (0.028 g, 0.2 mmol) and toluene (10 ml) were placed in a 20 ml pressure tube at 130 C (oil bath temperature)Under heating for 12 hours. The mixture was diluted with ethyl acetate, washed with H? O (2 x 20 ml), brine and dried over sodium sulfate. RemovedSolvent The crude product was purified by ISCO column chromatography using 5-10% ethyl acetate in hexanes as solvent to giveTo a solution of 2,2,2-trifluoro-1- [2- (3-phenyl-pyrazol-1-yl) -phenyl] -ethanol (75 mg).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Phenyl-1H-pyrazole, other downstream synthetic routes, hurry up and to see.