Adding a certain compound to certain chemical reactions, such as: 73387-46-9, name is 3-(4-Bromophenyl)-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 73387-46-9, Recommanded Product: 3-(4-Bromophenyl)-1H-pyrazole
(2) 3-(4-bromophenyl)-1-methylpyrazole and 5-(4-bromophenyl)-1-methylpyrazole Sodium hydride (0.43 g, 17.9 mmol) was added slowly to a solution of 3-(4-bromophenyl)-1H-pyrazole (1.0 g, 4.48 mmol) in 50 ml of THF under N2. The mixture was stirred for 1 h, then iodomethane (1.27 g, 8.97 mmol) was added to the suspension. The mixture was stirred at 23 for 2 h. Water (20 mL) was added and extracted with EtAc (50 mL¡Á3). The combined organic phase was washed with brine, dried, concentrated and purified by column chromatography to give 1.0 g of colorless liquid (mixture) (yield: 90%). LC-MS (Method B): m/z 237 (M+H) RT=1.62 min/2.5 min
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3-(4-Bromophenyl)-1H-pyrazole, and friends who are interested can also refer to it.