Electric Literature of 118430-73-2, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 118430-73-2 as follows.
To 1.0 g (6.53 mmol) of 5-tert-butyl-2-methyl-2H-pyrazol-3-ylamine in 10 mL of CH2Cl2 is added 1.37 g (7.17 mmol) of 4-isocyanate-benzoic acid ethyl ester, and the mixture is stirred at 23C for 3 hr. The white solid is filtered and triturated with methylene chloride and then with diethyl ether. The solids are air-dried 1 hr to obtain the title product (2.07 g, 6.01 mmol, 92 % yield, ES+(m/z) 345 [M+H]).
According to the analysis of related databases, 118430-73-2, the application of this compound in the production field has become more and more popular.