Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5334-39-4, name is 3-Methyl-4-nitro-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows., category: pyrazoles-derivatives
To a solution of 3-methyl-4-nitro-lH-pyrazole (3.81 g, 30.0 mmol) in DMF (20 mL) was added K2CO3 (8.28 g, 60.0 mmol) and diethyl 2-bromo-2-methylmalonate (9.10 g, 36.0 mmol). The mixture was stirred at 100 C for 20 h. The reaction mixture was then treated with H20 (500 mL), extracted with ethyl acetate (20 mL x 3). The organic layer was evaporated and the residue was purified by silica gel column chromatography eluting with petroleum ether/ethyl acetate (10/1) to afford the title compound (3.6 g, 41%) as oil. LC-MS (ESI): m z = 300 (M+H)+.
According to the analysis of related databases, 5334-39-4, the application of this compound in the production field has become more and more popular.