In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 4054-67-5 as follows. name: 3,3′,5,5′-Tetramethyl-1H,1’H-4,4′-bipyrazole
A mixture of H4L (0.05 mmol, 0.023 g), bpz (0.10 mmol, 0.020 g), Co(NO3)26H2O (0.15 mmol, 0.044 g) and 6mL of acetonitrile/H2O (v/v 1:1) was stirred for 30 min and then transferred and sealed in a 25mL Teflon-lined reactor and heated to 120 C for 72 h, and then cooled toroom temperature at a rate of 5 C/h. Red block crystals of 1 were obtained in 58% yield based on cobalt. Calcd (%) for C34H30N4O11Co2, C,51.79; H, 3.84; N, 7.11. Found C, 51.35; H, 3.49; N, 7.01. IR: 3393(vs);3176(m); 2933(m); 2355(m); 1605(v); 1524(m); 1443(v); 1261(m);1128(v); 1037(m); 774(m); 733(m).
According to the analysis of related databases, 4054-67-5, the application of this compound in the production field has become more and more popular.