Synthetic Route of 139756-02-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 139756-02-8, name is 4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
2) 1-methyl-3-propyl-4 – (2-propoxy benzamido- ) pyrazole-5-carboxamide preparation: heating 7.5mmol2-propoxy benzoyl chloride is dissolved in a 50 mu L methylene chloride, by adding 0.07g4-dimethyl aminopyridine, 0.5 ml triethylamine, stirring slowly dripping 6.8mmol4-amino-1-methyl-3-n-propyl -1H-pyrazole-5-carboxamide, microwave heating 100 C reaction 5 minutes, after the reaction of the organic solvent is removed by reduced pressure distillation, a small amount of ethanol re-crystallization, drying after filtration, a kind of white obtained 1-methyl-3-propyl-4 – (2-propoxy benzamido- ) pyrazole-5-carboxamide, the yield is 80-84%;
The synthetic route of 4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide has been constantly updated, and we look forward to future research findings.